TMS Therapy for Post-Stroke Recovery Treatment

Advanced Post-Stroke Therapy in Villanova & Horsham, PA and The Main Line Near Philadelphia

Stroke is a leading cause of long-term disability, with many survivors experiencing persistent challenges with movement, speech, swallowing, mood, and cognitive function. Traditional rehabilitation remains essential, but when recovery has plateaued or progress is slow, transcranial magnetic stimulation (TMS) offers an emerging complementary approach. At Complete Mind Care of PA, our experienced team of over 20 board-certified providers offers advanced neuromodulation treatments as part of comprehensive brain wellness care to support stroke recovery and rehabilitation.

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Why Choose Complete Mind Care of PA for Stroke Recovery?

Our leadership team brings extensive experience from building a successful 35-location TMS practice, giving us deep expertise in applying neuromodulation treatments to complex neurological conditions. We serve more than 4,500 active patients across our Horsham and Villanova locations with extended hours (7 AM – 8 PM weekdays) to accommodate your rehabilitation schedule.

We understand that stroke recovery is a long and challenging journey that affects every aspect of your life—your independence, relationships, work, and sense of self. Remission is our mission, and we’re committed to exploring every evidence-based approach to help you maximize recovery and quality of life. Our goal is getting you better and helping you return to the activities and connections that matter most.

Understanding Stroke and Its Long-Term Effects

Stroke occurs when blood supply to part of the brain is interrupted, either by a blocked vessel (ischemic stroke, approximately 87% of cases) or by bleeding in the brain (hemorrhagic stroke). Without adequate blood flow, brain cells are damaged or die, leading to various impairments depending on which areas are affected.

Common Post-Stroke Challenges

Stroke survivors often experience a range of persistent symptoms:

Motor Impairments: Weakness or paralysis on one side of the body (hemiparesis or hemiplegia), difficulty with arm and hand function, impaired walking and balance, reduced coordination and dexterity. Motor impairment affects 55-75% of stroke survivors.

Speech and Language Difficulties (Aphasia): Difficulty speaking, understanding language, reading, or writing. Affects approximately 30-38% of stroke survivors. Types include Broca’s aphasia (difficulty producing speech), Wernicke’s aphasia (difficulty understanding language), global aphasia (severe impairment in both), and other variants.

Swallowing Difficulties (Dysphagia): Trouble swallowing food or liquids safely, risk of aspiration and pneumonia, need for modified diets or feeding tubes. Affects 19-81% of stroke survivors initially, with many continuing to experience problems long-term.

Emotional and Cognitive Changes: Post-stroke depression (affects up to 30-50% of survivors), anxiety, emotional lability (sudden crying or laughing), cognitive impairment including memory problems and executive dysfunction, fatigue.

Other Complications: Spasticity (muscle stiffness and involuntary contractions), central post-stroke pain, unilateral spatial neglect (reduced awareness of one side of space), sensory deficits.

The Challenge of Incomplete Recovery

While the brain has remarkable capacity for recovery through neuroplasticity—forming new neural connections and reorganizing function—recovery often plateaus. Up to 50% of stroke survivors experience ongoing disability, and up to 30% still require assistance with daily activities six months after stroke. Traditional rehabilitation approaches include physical therapy, occupational therapy, speech therapy, and medications, but many individuals seek additional interventions to maximize recovery.

What Is TMS Therapy for Stroke Recovery?

Transcranial Magnetic Stimulation (TMS) uses focused magnetic pulses to modulate activity in specific brain regions affected by stroke. By influencing neural excitability and promoting adaptive neuroplasticity, TMS aims to enhance the brain’s natural recovery processes and improve rehabilitation outcomes.

Important Note: TMS for stroke recovery is an investigational treatment. It is not FDA-approved for any stroke-related indication. At Complete Mind Care of PA, we offer TMS for post-stroke symptoms based on emerging research evidence, provided as part of our comprehensive brain wellness approach on a cash-pay basis.

Research has explored TMS across multiple domains of stroke recovery including motor function, speech and language, swallowing, depression, cognition, and other sequelae. Studies primarily target either the affected (ipsilesional) hemisphere with excitatory stimulation or the unaffected (contralesional) hemisphere with inhibitory stimulation, based on theories of how the brain reorganizes after injury.

How TMS Works to Support Stroke Recovery

Stroke causes complex changes in brain organization extending beyond the damaged area. The injury disrupts not only local neural circuits but also communication between brain regions and interhemispheric balance.

Brain Reorganization After Stroke

Following stroke, several patterns emerge:

Interhemispheric imbalance: The unaffected hemisphere may become overactive, potentially inhibiting recovery in the damaged hemisphere through excessive interhemispheric inhibition.

Loss of function in damaged areas: The stroke lesion directly destroys neurons and connections responsible for specific functions.

Attempted compensation: Undamaged brain regions, including areas in both hemispheres, attempt to compensate for lost function, sometimes successfully and sometimes maladaptively.

Impaired neuroplasticity: While the brain tries to reorganize, this process may be incomplete or inefficient without intervention.

TMS Mechanisms for Recovery

TMS delivers magnetic pulses through a coil placed on the scalp, creating small electrical currents that modulate neural activity. Two main approaches are used:

High-frequency TMS (typically 5-20 Hz): Applied to the affected hemisphere to increase excitability and promote recovery of function in damaged but potentially viable brain tissue. This excitatory stimulation aims to “wake up” underactive regions and strengthen remaining neural pathways.

Low-frequency TMS (typically 1 Hz): Applied to the unaffected hemisphere to reduce its excessive activity and decrease inhibitory influence on the damaged hemisphere. This inhibitory stimulation aims to rebalance interhemispheric interactions.

Theta-burst stimulation (TBS): A newer, more efficient protocol that delivers bursts of stimulation in specific patterns. Continuous TBS (cTBS) has inhibitory effects while intermittent TBS (iTBS) has excitatory effects.

Research suggests TMS may support recovery through several mechanisms:

Enhanced neuroplasticity: Repeated stimulation promotes the formation of new synaptic connections and strengthens existing pathways, supporting functional reorganization.

Restoration of interhemispheric balance: By modulating activity in both hemispheres, TMS helps normalize communication patterns disrupted by stroke.

Improved network connectivity: Studies show TMS can enhance functional connectivity between brain regions, supporting more efficient information processing.

Synergy with rehabilitation: TMS may “prime” the brain to be more receptive to physical, occupational, and speech therapy, potentially amplifying rehabilitation benefits.

Current Research on TMS for Stroke Recovery

Extensive research has examined TMS for various aspects of stroke recovery, with evidence quality and consistency varying by symptom type.

Motor Function Recovery

Motor impairment is the most studied application of TMS in stroke. A 2024 systematic review and meta-analysis of high-quality randomized controlled trials found that TMS significantly improves upper extremity motor function, particularly when:

  • Treatment is provided within six months after stroke (subacute phase)
  • Patients have moderate to severe motor impairment at baseline
  • TMS is combined with conventional rehabilitation therapy

A landmark 2023 Dutch trial randomized 60 patients in the subacute phase (about 2 weeks post-stroke) to receive either active continuous theta-burst stimulation or sham stimulation over the unaffected motor cortex, along with regular rehabilitation. This study demonstrated statistically and clinically meaningful improvements across all outcome domains—motor impairment, motor function, and quality of life. Notably, this was one of the few stroke recovery studies to show active stimulation exceeding sham treatment in all measured aspects.

However, evidence remains mixed. Some well-designed studies have found no significant advantage of TMS over sham treatment. A comprehensive 2023 Stroke journal review noted that while promising, variability in protocols, timing, and patient characteristics makes it difficult to establish definitive conclusions about optimal treatment approaches.

Dysphagia (Swallowing Difficulties)

TMS for post-stroke dysphagia has shown consistently positive results. Multiple meta-analyses demonstrate that TMS significantly improves:

  • Overall swallowing function (moderate-quality evidence)
  • Penetration Aspiration Scale scores (reduced aspiration risk)
  • Activities of daily living
  • Quality of life related to eating and social participation

A 2022 meta-analysis of 10 studies with 246 patients found significant improvements in swallowing function with good acceptability and mild adverse effects. A 2024 umbrella review examining 19 systematic reviews found that all reported at least moderate overall effects favoring TMS for dysphagia improvement.

Both high-frequency stimulation of the affected hemisphere and low-frequency stimulation of the unaffected hemisphere have shown benefits, often in combination. The evidence supports TMS as a promising adjunctive treatment for post-stroke swallowing difficulties.

Aphasia (Speech and Language Impairment)

Research on TMS for aphasia recovery has produced encouraging results, particularly for non-fluent aphasia (including Broca’s aphasia). A 2024 meta-analysis of 47 randomized controlled trials with 2,190 patients found that TMS:

  • Improved aphasia severity scores (Aphasia Quotient)
  • Enhanced repetition and naming abilities
  • Improved spontaneous language production
  • Reduced co-occurring depression

The most studied approach involves low-frequency stimulation of the right inferior frontal gyrus (the right hemisphere homologue of Broca’s area) to reduce excessive compensatory activity that may hinder recovery. Some studies have also explored high-frequency stimulation of left hemisphere language areas.

While promising, optimal protocols for different aphasia types remain under investigation. The evidence suggests TMS works best when combined with speech-language therapy.

Post-Stroke Depression

Depression affects 30-50% of stroke survivors and significantly impairs rehabilitation participation and recovery. Several meta-analyses support the use of TMS for post-stroke depression, with effect sizes comparable to TMS for primary depression.

TMS for post-stroke depression typically targets the left dorsolateral prefrontal cortex with high-frequency stimulation, following the same protocols proven effective for major depressive disorder. This remains one of the strongest applications of TMS in stroke recovery, with evidence-based guidelines rating it as Level A evidence (proven effective).

Cognitive Function

Research on TMS for post-stroke cognitive impairment has shown variable results. Some studies report improvements in attention, memory, executive function, and processing speed, while others find no significant benefit. The heterogeneity in cognitive outcomes, stimulation protocols, and patient characteristics makes it difficult to draw definitive conclusions.

Current evidence suggests TMS may benefit specific cognitive domains in some individuals, but more research is needed to identify optimal protocols and which patients are most likely to benefit.

Other Post-Stroke Complications

Spasticity: Some evidence suggests TMS may reduce muscle stiffness and involuntary contractions, though results are mixed.

Central post-stroke pain: High-frequency stimulation of the primary motor cortex has shown promise for reducing chronic pain after stroke, following protocols used for other types of neuropathic pain.

Unilateral spatial neglect: Studies examining TMS for neglect (reduced awareness of one side of space) have shown mixed results. While some patients improve, optimal protocols remain unclear.

What to Expect During TMS Treatment for Stroke Recovery

Comprehensive Evaluation

Treatment begins with a thorough assessment by our board-certified psychiatrists or psychiatric nurse practitioners. We’ll review your stroke history (type, location, timing), current symptoms and functional limitations, rehabilitation progress to date, previous treatments tried, current medications and therapies, imaging results if available, and recovery goals.

We’ll conduct assessments relevant to your primary concerns, which may include motor function tests, speech and language evaluation, swallowing assessment, depression and mood screening, or cognitive function tests. We’ll also perform a motor threshold test to calibrate the TMS device to your individual physiology.

Given the investigational nature of TMS for stroke recovery, we’ll have an extensive discussion about realistic expectations, the current state of research evidence for your specific symptoms, and how TMS fits into your overall rehabilitation plan.

Treatment Protocol

TMS protocols for stroke recovery vary based on the symptoms being targeted and the timing since your stroke:

For motor recovery:

  • Typical approach: Low-frequency (1 Hz) inhibitory stimulation over the unaffected motor cortex, OR high-frequency (5-20 Hz) excitatory stimulation over the affected motor cortex, OR sequential bilateral stimulation
  • Daily sessions Monday through Friday for 2-6 weeks
  • Session duration: 20-40 minutes
  • Often combined with immediate physical or occupational therapy

For dysphagia:

  • High-frequency stimulation of affected swallowing cortex or low-frequency stimulation of unaffected side
  • Typically 10-20 sessions over 2-4 weeks
  • May target primary motor cortex areas representing swallowing muscles

For aphasia:

  • Most commonly: Low-frequency inhibitory stimulation over right inferior frontal gyrus
  • Alternatively: High-frequency stimulation of left hemisphere language areas
  • Usually 10-20 sessions over 2-4 weeks
  • Ideally combined with concurrent speech-language therapy

For post-stroke depression:

  • High-frequency (10 Hz) stimulation over left dorsolateral prefrontal cortex
  • Standard depression treatment protocol: daily sessions for 4-6 weeks

Our team will design a personalized protocol based on your specific symptoms, stroke characteristics, time since stroke, current rehabilitation efforts, and the latest evidence for your situation.

During Your Session

You’ll sit comfortably in a private treatment room while the TMS coil is positioned over your scalp using precise anatomical landmarks or, in some cases, neuronavigation guided by your brain imaging. The treatment produces clicking sounds and creates a tapping sensation on your head.

You’ll remain awake and alert throughout treatment. For motor recovery protocols, you may be asked to imagine or attempt movements, or engage in specific motor tasks. For speech protocols, you may work with speech materials. For other protocols, you may read, listen to music, or relax.

Most patients tolerate treatment well, though some experience mild scalp discomfort during the first few sessions. This typically diminishes after the first week.

Integration with Rehabilitation

TMS should be viewed as a tool to enhance—not replace—conventional rehabilitation. The strongest evidence emerges when TMS is combined with appropriate therapy:

  • Motor TMS works best when followed immediately by physical or occupational therapy
  • Speech TMS shows optimal results when paired with speech-language therapy sessions
  • Swallowing TMS often incorporates swallowing exercises or feeding trials

We work closely with your rehabilitation team to coordinate timing and ensure TMS complements your ongoing therapies.

Monitoring Progress

We use standardized assessments to track changes in your targeted symptoms:

  • Motor function: Fugl-Meyer Assessment, Action Research Arm Test, walking speed, grip strength
  • Dysphagia: Swallowing function scales, aspiration measures, dietary level
  • Aphasia: Aphasia quotient, naming tests, language comprehension tasks
  • Depression: Standard depression rating scales
  • Functional outcomes: Activities of daily living, quality of life measures

Regular check-ins help us understand how treatment affects your day-to-day function and adjust protocols as needed.

Timeline for Improvement

If benefits occur, they typically emerge gradually over weeks of treatment. The timeline varies by symptom type and individual factors:

Motor function: Most improvement seen after 2-4 weeks of combined TMS and therapy, with continued gains during ongoing rehabilitation.

Dysphagia: Improvements may appear within 2-3 weeks, with functional swallowing gains continuing after treatment completion.

Aphasia: Language improvements often emerge gradually over 2-4 weeks, particularly when TMS is combined with speech therapy.

Depression: Similar timeline to depression treatment generally—noticeable improvement after 2-4 weeks, maximum benefit after 4-6 weeks.

Effects may continue to build after the treatment course ends, particularly when TMS has enhanced neuroplasticity that supports ongoing rehabilitation efforts.

Is TMS Right for Your Stroke Recovery?

Potential Candidates

TMS may be appropriate if you:

  • Have experienced an ischemic or hemorrhagic stroke with persistent symptoms affecting motor function, speech, swallowing, mood, or cognition
  • Are in the subacute phase (weeks to months post-stroke) or chronic phase (months to years post-stroke), with subacute phase potentially showing stronger benefits
  • Continue to experience functional limitations despite conventional rehabilitation
  • Are engaged in or willing to engage in appropriate rehabilitation therapies (physical, occupational, speech therapy)
  • Have specific, measurable goals for recovery
  • Are on a stable medical and medication regimen
  • Are able to commit to daily weekday appointments for 2-6 weeks
  • Prefer to explore complementary approaches alongside standard care
  • Have no contraindications to TMS (see below)

TMS May Not Be Appropriate With

  • Implanted metallic or electronic devices in or near the head (cochlear implants, deep brain stimulators, vagus nerve stimulators, aneurysm clips, bullet fragments)
  • History of seizures (discuss with our team—not always an absolute contraindication, but requires careful evaluation)
  • Pregnancy (limited safety data available)
  • Active medical instability related to stroke
  • Medications that significantly lower seizure threshold (discuss with team)

Important Considerations

FDA approval status: TMS for stroke recovery is investigational and not FDA-approved for any stroke-related indication. Research evidence varies by symptom type, with some areas (dysphagia, certain aspects of motor recovery, post-stroke depression) showing more consistent benefits than others.

Insurance coverage: TMS for stroke recovery is generally not covered by insurance as it is an investigational indication. Treatment is provided on a cash-pay basis.

Timing matters: Evidence suggests TMS may be more effective when provided in the subacute phase (first weeks to months after stroke) rather than in very chronic stages. However, benefits have been reported even years after stroke.

Essential to combine with rehab: TMS is not a standalone treatment. It works best as part of a comprehensive rehabilitation program including appropriate physical, occupational, and/or speech therapy. The strongest evidence comes from studies combining TMS with conventional rehabilitation.

Variable response: Individual responses to TMS for stroke recovery vary significantly. Some individuals experience meaningful functional improvements while others see modest or no benefits. Factors affecting response may include stroke location and size, time since stroke, baseline severity, age, and individual neuroplasticity capacity.

Research still evolving: While TMS has Level A evidence for upper limb motor recovery and post-stroke depression according to some guidelines, optimal protocols (stimulation site, frequency, intensity, duration) for different post-stroke symptoms remain under active investigation. Treatment approaches continue to be refined as new research emerges.

Part of the recovery journey: Stroke recovery is measured in months and years, not days or weeks. TMS represents one tool in a comprehensive, long-term rehabilitation approach. Realistic expectations are essential.

Our Compassionate, Recovery-Focused Approach

We recognize that recovering from a stroke fundamentally changes your life and identity. The frustration of not being able to move, speak, swallow, or think as you once did creates profound challenges. Stroke survivors often describe feeling trapped in a body that no longer responds as it should, or struggling to express thoughts that are clear in their minds.

Our team provides patient-centered care that honors your individual recovery journey and treatment preferences. We understand that progress isn’t always linear—you’ll experience good days and difficult days, breakthroughs and plateaus. We’re here to support you through this process.

Our comfortable, private treatment rooms offer a calm environment designed to support recovery and minimize stress. We work closely with you and your rehabilitation team to ensure that TMS integrates effectively with your overall recovery plan.

All TMS sessions are supervised by our trained clinical staff with immediate access to our board-certified psychiatric providers who have experience in both brain stimulation and caring for individuals recovering from neurological injuries.

Pricing Information

Cash-Pay Treatment: TMS for stroke recovery is not covered by insurance as it is an investigational indication. Treatment is provided on a self-pay basis.

We provide transparent pricing information during your consultation, including the cost of the comprehensive evaluation, treatment sessions, and follow-up care. Our team will work with you to understand the financial commitment and help you make an informed decision about pursuing this investigational treatment as part of your recovery journey.

Ready to Explore TMS for Stroke Recovery?

If you’re working to recover from a stroke and seeking complementary approaches to maximize your rehabilitation outcomes, we’re here to help you understand whether TMS might be an appropriate addition to your recovery plan.

We serve patients throughout Montgomery and Delaware Counties, including communities along the Main Line, Abington, Dresher, and surrounding areas.

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Frequently Asked Questions About TMS for Stroke Recovery

Is TMS FDA-approved for stroke recovery?

No. TMS for stroke recovery is an investigational treatment. TMS is FDA-approved for treatment-resistant depression, obsessive-compulsive disorder, certain types of migraines, and smoking cessation, but not for any stroke-related indications. However, research has established Level A evidence (proven effective) for TMS in upper limb motor recovery and post-stroke depression according to some evidence-based guidelines, indicating strong research support even without FDA approval for this specific indication.

The timeline varies depending on which symptoms are being targeted and individual factors. Most people who respond notice gradual improvements over 2-4 weeks of daily treatment. Motor and swallowing improvements may continue during ongoing rehabilitation after TMS treatment ends. Language recovery often occurs gradually over weeks to months when TMS is combined with speech therapy. Post-stroke depression typically improves on a similar timeline to depression treatment generally—after 2-4 weeks of treatment.

Research has examined TMS in both subacute (weeks to months post-stroke) and chronic (months to years post-stroke) patients. Evidence suggests TMS may be somewhat more effective in the subacute phase when neuroplasticity is most active. However, benefits have been reported in individuals many years post-stroke, particularly when combined with intensive rehabilitation. During your consultation, we’ll discuss realistic expectations based on your specific timing and circumstances.

No. TMS should never replace conventional rehabilitation. The strongest evidence for TMS comes from studies where it was provided alongside—not instead of—traditional therapy. TMS appears to work by enhancing neuroplasticity and “priming” the brain to be more receptive to rehabilitation. Think of it as a tool that may amplify the benefits of the essential work you’re doing in physical, occupational, and speech therapy.

The strongest and most consistent evidence supports TMS for:

  • Post-stroke dysphagia (swallowing difficulties) – consistently positive results across multiple studies
  • Upper extremity motor recovery – particularly in subacute phase and moderate to severe impairment
  • Post-stroke depression – strong evidence, rated Level A in guidelines
  • Non-fluent aphasia (speech difficulties) – promising results when combined with speech therapy

Evidence is more mixed for cognitive impairment, spasticity, pain, and neglect. We’ll discuss the specific evidence for your symptoms during consultation.

TMS primarily targets brain function rather than muscles directly. By modulating activity in motor regions of the brain, TMS can influence function on the opposite side of the body (the brain’s right hemisphere controls the left side of the body and vice versa). For motor recovery, treatment might involve stimulating the affected brain hemisphere, suppressing the unaffected hemisphere, or sequential bilateral stimulation. Your specific protocol will be tailored to your stroke location and symptoms.

Yes. Extensive research demonstrates that TMS is safe and well-tolerated in stroke survivors, including those with both ischemic and hemorrhagic strokes. The rate of TMS-related seizures in stroke patients is very low (less than 1% overall, similar to other populations). Common side effects are mild—temporary scalp discomfort, mild headache during early sessions, or facial muscle twitching during treatment. TMS has been successfully used in thousands of stroke survivors in research settings and clinical practice.
When improvement occurs, durability varies by individual and symptom type. Motor and functional gains achieved during TMS treatment often persist and may continue to build with ongoing rehabilitation. Language improvements similarly tend to maintain when supported by continued speech therapy. Depression improvements typically last months, with maintenance sessions or repeat courses sometimes used if symptoms return. The key is viewing TMS as a catalyst for neuroplastic change that then gets reinforced and built upon through continued rehabilitation and real-world practice.

No. Because TMS for stroke recovery is investigational and not FDA-approved for stroke indications, it is not covered by insurance. Treatment must be paid out-of-pocket. We provide transparent pricing during your consultation so you can make an informed decision about this investment in your recovery.

TMS is one of several emerging neuromodulation approaches being studied for stroke recovery. Other techniques include transcranial direct current stimulation (tDCS), vagus nerve stimulation, and epidural cortical stimulation. Each has different mechanisms, evidence bases, and practical considerations. TMS offers the advantages of being non-invasive, well-tolerated, and having a substantial research base. During consultation, we can discuss how TMS compares to other options you may be considering.

Patients often have multiple post-stroke impairments. We can discuss whether to focus TMS treatment on your most limiting symptom or, in some cases, whether sequential treatment courses targeting different symptoms might be appropriate. Your overall rehabilitation schedule and priorities will guide this decision. The most important principle is that TMS should be coordinated with your specific therapy needs—motor TMS with physical/occupational therapy, speech TMS with speech-language therapy.

Scientific Resources and Research on TMS for Stroke Recovery

Learn more about the research on transcranial magnetic stimulation for stroke recovery:

Disclaimer: TMS for stroke recovery is an investigational treatment approach and is not FDA-approved for any stroke-related indication. Evidence quality and consistency vary by symptom type. Individual outcomes vary significantly. TMS should be used as part of comprehensive rehabilitation including appropriate physical, occupational, and/or speech therapy. This information is for educational purposes and does not constitute medical advice. Consult with qualified healthcare providers specializing in stroke rehabilitation to determine if TMS is appropriate for your situation.

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Serving the Philadelphia Suburbs and Main Line

Located in Horsham and Villanova, we serve patients across Montgomery and Delaware Counties, including the Main Line, Abington, Dresher, and surrounding communities. Our extended hours—including early morning and evening appointments—make expert care accessible when you need it.

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Complete Mind Care was founded on the premise of providing full mental health support delivered by a team of expert professionals, in the comfort of a world-class facility local to you—so you can build a foundation for lasting recovery close to home. Plus 40+ additional insurance carriers accepted.

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